Largest genomic study on type 2 diabetes in sub-Saharan African populations

Researchers have performed the largest GWAS study on type 2 diabetes in the sub-Saharan African populations, revealing an association between the disease and previously unlinked ZRANB3 gene. By using animal models, their results show that dysfunction of the ZRANB3 gene has major repercussions on insulin production. This link may hold key answers to the treatment of type 2 diabetes in all populations.